Peptide receptor radionuclide therapy (PRRT) in Germany
Innovative treatment of neuroendocrine tumors in Germany
Peptide receptor radionuclide therapy (PRRT) is an advanced method for the treatment of neuroendocrine tumors (NETs), combining high selectivity with a powerful therapeutic effect. This technology is used in patients with progressive, difficult to resect tumors, especially those with advanced disease. At the RheinRegio Klinik Zentrum, PRRT is carried out in full compliance with European protocols and using the latest achievements of medical science
What is PRRT: description of the method
PRRT is targeted radiation therapy based on the use of radionuclide drugs that specifically affect tumor cells. The targets are somatostatin receptors present on the surface of neuroendocrine cells. The radioactive isotope (most often ^177Lu) binds to somatostatin analogues and accumulates directly in tumor tissues, minimizing damage to healthy cells.
The method is based on the systemic administration of a radiopharmaceutical, which spreads throughout the body and concentrates in areas with high receptor expression. Next, a localized effect of radiation occurs, which makes it possible to destroy tumor cells and stop the growth of metastases.
Indications for PRRT
PRRT is indicated for patients with neuroendocrine tumors of various locations, including:
- gastroenteropancreatic NETs;
- bronchopulmonary tumors;
- tumors that produce hormones.
The method is especially effective in cases of high expression of somatostatin receptors and the presence of a progressive course of the disease, when other types of treatment (surgery, chemotherapy) have been insufficient.
Contraindications
Contraindications to PRRT include:
- severe renal failure;
- severe forms of leukopenia and thrombocytopenia;
- absence of somatostatin receptors in tumor tissues;
- pregnancy and lactation period.
Before starting therapy, RheinRegio Klinik Zentrum performs a thorough and complete diagnosis, including scintigraphy using octreotides and CT/MRI, which allows us to accurately determine the patient’s suitability for this type of treatment.
Each direction is supervised by advanced oncologists.
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PRRT in Germany: the RheinRegio Klinik Zentrum approach
At RheinRegio Klinik Zentrum, patients receive an individual treatment protocol based on the results of PET-CT and molecular genetic studies. The drugs used, such as ^177Lu-DOTATATE, are highly effective and safe.
The PRRT procedure is carried out in several courses at intervals of 6–10 weeks. The entire process is accompanied by constant monitoring of the patient’s condition, support at all stages of treatment and adaptation of the treatment plan as necessary. The clinic provides 100% confidentiality and the highest level of service.
Our clinics
The association of clinics RheinRegio Klinik Zentrum offers the organization of lymphoma treatment in Germany without intermediaries, providing access to the country’s leading oncology clinics. We combine advanced techniques, an individual approach and the highest level of medical care, giving hope even in difficult cases.
Why RheinRegio Klinik Zentrum?
- World-class health proffesionals with unique experience in the treatment of neuroendocrine tumors.
- The most modern equipment, meeting international nuclear medicine standards.
- The highest level of technology and pharmaceuticals, including original radiopharmaceuticals.
- Friendly and helpful staff, providing a comfortable atmosphere and attention to each patient.
- Latest advances in medical science in the field of PRRT and targeted therapy.
- Thorough and complete diagnosis, allowing you to accurately select a therapeutic protocol.
- Support at all stages of treatment, including monitoring after completion of therapy.
- The highest level of service and clear coordination of all procedures without waiting or queuing.
PRRT is not just a treatment method, but a chance to improve the quality of life and prolong it even in the later stages of the disease. At RheinRegio Klinik Zentrum you have access to cutting-edge therapy with an attention to detail that is changing the standard of cancer care.
