Treatment of thyroid carcinoma in Germany
Innovations in the treatment of thyroid carcinoma: from fine-needle biopsy to targeted therapy
Thyroid carcinoma is one of the most curable types of cancer if diagnosed early. RheinRegio Klinik Zentrum uses innovative treatment protocols, including robotic thyroidectomy, radioiodine therapy and targeted therapy, which allows us to achieve high survival rates even in aggressive forms of the disease.
Symptoms of thyroid carcinoma
In the early stages, the disease is often asymptomatic. As it develops, the following may appear:
- Nodule in the neck area, noticeable on palpation
- Enlarged lymph nodes in the neck
- Hoarseness of voice for no obvious reason
- Difficulty swallowing or breathing
- Pain in the front of the neck
- Unreasonable cough
If these symptoms are present, it is recommended to immediately undergo examination by an endocrinologist.
Diagnosis of thyroid carcinoma at the RheinRegio Klinik Zentrum
We conduct a comprehensive examination:
- Ultrasound of the thyroid gland with elastography
- Ultrasound-guided fine-needle biopsy
- Calcitonin test (if medullary cancer is suspected)
- CT/MRI with contrast to assess extent
- PET-CT for suspected metastases
- Genetic testing of RET proto-oncogene
Our endocrinologist-oncologists use the latest diagnostic algorithms to accurately determine the type and stage of the tumor.
Each direction is supervised by advanced oncologists.
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Classification and stages of thyroid carcinoma
Classification by histological type:
- Papillary (70-80% of cases) – least aggressive
- Follicular (10-15%) – often metastasizes to the lungs and bones
- Medullary (5-7%) – hereditary form
- Anaplastic (1-2%) – the most aggressive
The stages are determined according to the TNM system:
- Stage I: tumor ≤2 cm without metastases
- Stage II: tumor 2-4 cm or minimal spread
- Stage III: lymph node involvement
- Stage IV: distant metastases
Treatment options for thyroid carcinoma
Surgical treatment
- Hemithyroidectomy – for small tumors
- Total thyroidectomy – for aggressive forms
- Lymph node dissection – if lymph nodes are affected
Radioiodine therapy (I-131)
- Destruction of residual cells after surgery
- Treatment of metastases
Targeted therapy
- Lenvatinib, Sorafenib – for advanced cancer
- Selpercatinib – for RET-mutated medullary cancer
Hormone replacement therapy
- Selection of the optimal dose of L-thyroxine
- Lifelong TSH monitoring
Survival prognosis
- Papillary carcinoma (I–II stage): 95–100% 10 year survival rate
- Follicular carcinoma: 85–90% (in the absence of distant metastases)
- Medullary carcinoma: 70–80% (depends on mutation RET)
- Anaplastic carcinoma: <10% (aggressive course)
Thyroid carcinoma is not a death sentence. At RheinRegio Klinik Zentrum we use innovative technologies to provide our patients with a complete cure and a high quality of life.
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Our clinics
The association of clinics RheinRegio Klinik Zentrum offers the organization of treatment of thyroid carcinoma in Germany without intermediaries, providing access to the country’s leading oncology clinics. We combine advanced techniques, an individual approach and the highest level of medical care, giving hope even in difficult cases.
Why RheinRegio Klinik Zentrum?
- Experienced endocrine surgeons – more than 200 operations annually
- Modern robotic systems – minimal trauma
- Individual radioiodine therapy regimens – accurate dosage calculation
- Molecular genetic laboratory – personalized approach
- Lifelong follow-up – monitoring relapses
