Treatment of bronchial carcinoma in Germany
Innovations in the treatment of bronchial carcinoma: from fluid biopsy to third-generation targeted drugs

Bronchial carcinoma is a malignant neoplasm that develops from the bronchial epithelium. RheinRegio Klinik Zentrum uses innovative treatment protocols, including robotic surgery, targeted therapy and immuno-oncology drugs, which allows achieving high results even in late stages of the disease.
Symptoms of bronchial carcinoma
The clinical picture depends on the location of the tumor:
Central cancer (70% of cases):
- Boring cough for no apparent reason
- Hemoptysis (in 40% of cases)
- Progressive shortness of breath
- Recurrent pneumonia
- Chest pain
Peripheral cancer:
- Long asymptomatic course
- Pain during pleural invasion
- Pancoast syndrome (at the apex of the lung)
- Paraneoplastic syndromes
Diagnosis of bronchial carcinoma at the RheinRegio Klinik Zentrum
- CT scan of the chest with contrast
- Bronchoscopy with biopsy and sputum cytology
- Whole body PET-CT
- Molecular genetic testing (EGFR, ALK, ROS1, PD-L1)
- Endobronchial ultrasound (EBUS) for lymph node assessment
- Thoracoscopic biopsy for peripheral formations
Each direction is supervised by advanced oncologists.
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Classification and stages of bronchial carcinoma
Histological types:
- Squamous (40-50%)
- Adenocarcinoma (30-35%)
- Small cell (10-15%)
- Large cell (5-10%)
Staging according to TNM 8th revision:
- Stage I: tumor ≤4 cm without lymph node involvement
- Stage II: tumor >4 cm or damage to peribronchial lymph nodes
- Stage III: locally advanced process
- Stage IV: distant metastases
Treatment methods for bronchial carcinoma
Surgical treatment:
- Video-assisted lobectomy/bilobectomy
- Circular resection of the bronchus in early forms
- Extended operations for locally advanced process
Radiation therapy:
- Stereotactic radiosurgery (CyberKnife)
- Proton therapy for gentle radiation
Systemic therapy:
- Targeted drugs (Osimertinib, Alectinib)
- Immunotherapy (Pembrolizumab, Nivolumab)
- Chemoradiation therapy according to ESMO protocols
Survival prognosis
Bronchial carcinoma requires a multidisciplinary approach. At RheinRegio Klinik Zentrum we offer innovative treatment methods based on a personalized approach to each patient.
Make an appointment with a pulmonary oncologist!
Why RheinRegio Klinik Zentrum?

- Thoracic surgeons with experience >500 resections
- Da Vinci robot for precision operations
- Own molecular diagnostics center
- Individual treatment regimens according to the latest recommendations
- International clinical trials












