Treatment of ductal cancer in Germany
Modern standards of treatment for DCIS and invasive forms with breast conservation

Ductal cancer (carcinoma) of the breast is the most common type of breast cancer, developing from the epithelium of the milk ducts. At RheinRegio Klinik Zentrum, personalized protocols are used to treat both non-invasive (DCIS) and invasive forms, combining oncological radicality with aesthetic reconstruction.
Symptoms of ductal cancer
Non-invasive form (DCIS)
- Often asymptomatic
- Microcalcifications on mammogram (80% of cases)
- Rarely – nipple discharge
Invasive form
- Palpable lump (firm, with jagged edges)
- Retraction of the skin or nipple
- Skin hyperemia (“lemon peel”)
- Enlarged axillary lymph nodes
Important: 20% of DCIS are detected incidentally during routine mammography.
Diagnosis of ductal cancer at RheinRegio Klinik Zentrum
At RheinRegio Klinik Zentrum we carry out:
- Digital mammography with tomosynthesis
- MRI of the mammary glands (for dense breast tissue)
- Stereotactic biopsy with determination of:
- ER/PR/HER2 receptors
- Index Ki-67
- Sentinel biopsy (for invasive forms)
- Genetic testing (BRCA1/2 if family history)
Innovation: Liquid biopsy for monitoring relapses.
Each direction is supervised by advanced oncologists.
Find out the cost of treatment
To find out the approximate cost of treatment, answer a few questions and we will contact you!
Classification and stages of ductal cancer
Histological variants
- DCIS (ductal carcinoma in situ)
- Invasive ductal carcinoma (80% of all breast cancers)
TNM stages
- 0: DCIS (Tis)
- I: Tumor ≤2 cm without metastases
- III: Involvement of 4-9 lymph nodes
Treatment methods for ductal cancer
1. Surgical treatment
- Lumpectomy (organ conserving surgery for DCIS)
- Oncoplastic resection with simultaneous reconstruction
- Skin/nipple sparing mastectomy
2. Radiation therapy
- APBI (accelerated partial irradiation)
- IMRT (gentle mode)
3. Systemic therapy
- Tamoxifen (for ER+)
- Trastuzumab (for HER2+)
- Olaparib (for BRCA mutations)
Survival prognosis
- DCIS: 98-100%
- Stage I: 90-95%
- Stage III: 70-75%
Conclusion: Our clinic uses a personalized approach to each patient.
Schedule a consultation to develop a personalized treatment plan.
Why RheinRegio Klinik Zentrum?

- Center for Oncoplastic Surgery – breast conservation in 70% of cases
- Individual radiation therapy regimens
- Genetic counseling
- Breast reconstruction (implants/flaps)












