Treatment of hemangiopericytoma in Germany
Innovative methods of therapy: from accurate diagnosis to targeted therapy
Hemangiopericytoma is a rare vascular tumor arising from pericytes (cells surrounding capillaries). It can be benign or malignant and often recurs and metastasizes. RheinRegio Klinik Zentrum uses innovative treatment protocols, including radical resection, stereotactic radiosurgery and targeted therapy.
Features:
✔ Most often occurs in soft tissues (extremities, retroperitoneum)
✔ In 15–30% of cases it is localized in the central nervous system (meninges)
✔ Can be benign (low-grade malignancy) or aggressive (with metastases to the lungs, bones)
✔ In 40% of cases it recurs after removal
Symptoms of hemangiopericytoma
Manifestations depend on localization:
1. Soft tissue hemangiopericytoma
- Painless, firm formation under the skin
- Swelling and dysfunction of the limb (for large sizes)
- Blueness of the skin (due to the vascular component of the tumor)
2. Hemangiopericytoma of the brain
- Headaches (worsen in the morning)
- Nausea, vomiting
- Convulsions
- Focal neurological symptoms (paresis, speech impairment)
3. Hemangiopericytoma of the lungs or abdominal cavity
- Shortness of breath (with lung damage)
- Intestinal obstruction (with retroperitoneal localization)
Diagnosis of hemangiopericytoma at RheinRegio Klinik Zentrum
- MRI with contrast is the gold standard for brain and soft tissue tumors
- CT scan of the chest/abdomen – search for metastases
- Biopsy with immunohistochemistry (markers: CD34, STAT6, bcl-2)
- PET-CT – assessment of tumor metabolic activity
Each direction is supervised by advanced oncologists.
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Classification and stages of hemangiopericytoma
1. Low degree of malignancy
- Growth: Slow
- Mitoses: <1 for 10 fields of view
- Necrosis: None
- Metastases: Rarely
2. High degree of malignancy
- Growth: Fast
- Mitoses: >4 for 10 fields of view
- Necrosis: Present
- Metastases: Up to 50% of cases
Treatment methods for hemangiopericytoma
1. Surgery
- Radical resection involving healthy tissue is the main method
- Neuronavigation and intraoperative MRI for brain tumors
2. Radiation therapy
- Stereotactic radiosurgery (CyberKnife) for inoperable cases
- Proton therapy for relapses
3. Targeted therapy
- Sunetinib (angiogenesis inhibitor)
- Bevacizumab for metastases
Survival prognosis
- Localized forms – 80–90%
- Metastatic form – 45–60%
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Our clinics
The association of clinics RheinRegio Klinik Zentrum offers the organization of treatment of hemangiopericytoma in Germany without intermediaries, providing access to the country’s leading oncology clinics. We combine advanced techniques, an individual approach and the highest level of medical care, giving hope even in difficult cases.
Why RheinRegio Klinik Zentrum?
- Sarcoma Experts – 25+ years of experience treating rare tumors
- Da Vinci robot – precision operations in hard-to-reach areas
- Genetic profile of the tumor – selection of personalized therapy
- Clinical trials – access to innovative drugs
