Treatment of lung cancer in Germany

Innovative therapies: from early diagnosis to personalized treatment

Lung cancer is one of the most aggressive cancers, ranking first in mortality among all types of cancer. RheinRegio Klinik Zentrum uses modern diagnostic and treatment methods, including minimally invasive surgery, targeted therapy and immuno-oncology. Our goal is to maximize the life of patients and improve its quality even in late stages.

Symptoms of lung cancer

  • Early signs (often absent)

    • Prolonged cough (more than 2-3 weeks)
    • Shortness of breath with normal exertion
    • Chest pain that gets worse with deep breaths
    • Decreased appetite and unexplained weight loss

    Late symptoms

    • Hemoptysis (blood in the sputum)
    • Wheezing and hoarseness (recurrent nerve damage)
    • Swelling of the face and neck (superior vena cava syndrome)
    • Frequent pneumonia (due to bronchial obstruction)

    Important: In 15% of patients, cancer is discovered accidentally during a chest x-ray.

Diagnosis of lung cancer at RheinRegio Klinik Zentrum

RheinRegio Klinik Zentrum uses high-precision methods:

  • Low-dose CT – screening for smokers (reduces mortality by 20%).
  • PET-CT – detection of metastases from 4 mm in size.
  • Bronchoscopy with biopsy + histological examination.

Genetic tests:

  • Mutations of EGFR, ALK, ROS1 – for selection of targeted therapy.
  • PD-L1 – determination of sensitivity to immunotherapy.

Important: The diagnostic accuracy in our clinics reaches 98% thanks to the use of advanced methods.

Find out the cost of treatment

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    Classification and stages of leukemia

    Main types of lung cancer

    • Non-small cell lung cancer (NSCLC, 80-85%):
      • Adenocarcinoma (more common in non-smokers)
      • Squamous cell carcinoma (smoking-related)
    • Small cell lung cancer (SCLC, 15-20%) – aggressive form with early metastasis.

    Stages according to the TNM system

    • Stage I: Tumor up to 4 cm without lymph node involvement (T1-2, N0, M0)
    • Stage II:
      • Tumor >4 cm without lymph node involvement (T2b-3, N0, M0)
      • OR tumor of any size with metastases to nearby lymph nodes (T1-2, N1, M0)
    • Stage III: Locally advanced process (T1-4, N2-3, M0)
    • Stage IV: Distant metastases (any T and N, M1)

    Lung cancer treatment methods

    • Surgical treatment (for stages I-II):
      • Lobectomy – removal of a lobe of the lung (using the Da Vinci robot)
      • Sublinary resection is an organ-conserving operation for small peripheral tumors
    • Radiation therapy:
      • Stereotactic radiosurgery (CyberKnife) – high-precision irradiation of inoperable tumors
      • Proton therapy is a modern method with minimal impact on healthy tissue
    • Systemic therapy:
      • Targeted drugs (eg, osimertinib for EGFR mutations)
      • Immunotherapy (pembrolizumab for PD-L1 expression >50%)
      • Chemoradiation treatment is the standard approach for small cell lung cancer (SCLC)
    • Palliative care:
      • Bronchial stenting for tumor obstruction of the airways
      • Pain relief according to the WHO three-step scheme (WHO protocol)

    Survival prognosis

    • Stage I – 60-80% 5-year survival rate.
    • Stage III – 15-30% (with combined treatment).
    • Stage IV – 2% (but with immunotherapy up to 25 months of life).

    Factors for improving prognosis:

    • Early diagnosis (CT screening for risk groups).
    • Presence of drug-resistant mutations (EGFR, ALK).

    Why choose Germany?

    • Leader in the treatment of lung cancer (5-year survival rate is 10-15% higher than the world average).
    • Financial transparency – fixed cost of treatment.

    At RheinRegio Klinik Zentrum, individual protocols are used for each patient. We combine advanced technology with decades of experience in the fight against lung cancer.

    Sign up for a consultation – we are ready to help even in difficult cases!

    Our clinics

    The association of clinics RheinRegio Klinik Zentrum offers cancer treatment in Germany without intermediaries, providing access to the country’s leading oncology clinics. We combine advanced techniques, an individual approach and the highest level of medical care, giving hope even in difficult cases.

    Catholic Clinical Complex

    The clinic specializes in the diagnosis and medical treatment of tumor diseases of internal organs (solid tumors and carcinomas), connective and musculoskeletal tissues (so-called sarcomas), as well as diseases of the blood and lymphatic system (lymphoma and leukemia). It conducts a wide range of clinical studies aimed at developing new drugs and vaccines for the treatment of cancer.

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    Rhine Clinical Complex Hospital Lucas

    The Lucas Clinic plays a key role in the German healthcare system, offering a wide range of medical services. All diagnostic and therapeutic radiological activities are carried out at the Institute of Clinical Radiology. Using the most modern devices, in accordance with the latest medical advances, low-irradiation methods of radiation therapy are used.

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    Sana’a Clinical Complex

    The Sanaa Clinical Complex actively uses the latest medical technologies in the treatment of cancer, including robotic surgical systems, high-precision diagnostics and innovative methods of radiation and chemotherapy.

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    Our oncologists:

    Bjorn-Wieland Lisboa

    Gynecologist, senologist, specialist in the treatment of breast cancer, Doctor of Medical Sciences…

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    Karl-Axel Hartmann

    A leading specialist in radiation therapy, Professor, Doctor of Medical Sciences, is included in the TOP list of the best German doctors…

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    Tobias Heintges

    Prof., dr. honey. Sciences, oncologist, gastroenterologist. Included in the TOP list of the best doctors in Germany according to the results of the annual survey of the public journalistic magazine “FOCUS”

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    Jörg Falbrede

    Gynecologist, oncologist, mammologist, uro-gynecologist, professor, doctor of medical sciences Jörg Falbrede is included in the TOP list of the best gynecologists in Germany…

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    Aristotle Giagounidis

    Professor, Doctor of Medical Sciences, Head of the Clinic of Oncology and Hematology Medicine, is on the TOP list of the best German oncologists…

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    Jan Martin Beron

    Dr. med. Jan Martin Beron, leading specialist in thoracic surgery. Specializes in the treatment of lung tumors, including lung cancer and metastases…

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    Thomas Dirschka

    Dermatologist, onco-dermatologist, specialist in allergology and venereology, professor, doctor of medical sciences…

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    Susan Ingman

    Radiologist, Diagnostic Radiologist, Nuclear Medicine Specialist, Dr. Susan Ingman, MD

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    Why RheinRegio Klinik Zentrum?

    • Interdisciplinary council: oncologists, surgeons and radiologists jointly develop an individual treatment plan
    • Genetic passport of the tumor: personalized selection of therapy based on the molecular profile of the tumor
    • Minimally invasive surgeries: modern surgical techniques reduce the rehabilitation period to 5-7 days
    • Clinical studies: access to innovative drugs (including amtivanamtab) within the framework of international protocols
    • 24/7 support: comprehensive assistance in organizing treatment for foreign patients

    Application for treatment

    Apply now, and our highly qualified staff quickly and professionally choose specialized clinics and physician and prepare visa invitation from the clinic. Application processing time varies from a few hours to 2-3 working days (depending on the complexity of the inquiry).