Treatment of nose cancer in Germany
An integrated approach to rhino-oncology: from organ-preserving operations to reconstruction
Cancer of the nose and paranasal sinuses accounts for 3% of all head and neck tumors. RheinRegio Klinik Zentrum uses innovative protocols combining endoscopic surgery, proton therapy and microsurgical reconstruction. Our goal is radical tumor removal while maintaining respiratory function and facial aesthetics.
Symptoms of nose cancer
Early signs
- Nasal congestion (unilateral, progressive)
- Purulent-bloody discharge
- Pain in the upper jaw/teeth
Late manifestations
- Facial skeleton deformity
- Diplopia (with growth into the orbit)
- Trigeminal neuralgia
- Enlarged cervical lymph nodes
Red flag: Unilateral symptoms unresponsive to standard therapy for more than 3 weeks.
Diagnosis of nasal cancer at RheinRegio Klinik Zentrum
At RheinRegio Klinik Zentrum we carry out:
- Nasal endoscopy with NBI + biopsy
- MRI with DWI sequence (assessment of invasion)
- PET-CT (detection of distant metastases)
- Molecular tests:
- PD-L1 status (for immunotherapy)
- HPV status (prognostic factor)
Innovation: 3D navigation for resection planning.
Each direction is supervised by advanced oncologists.
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Classification and stages of nasal cancer
Histological types
- Squamous cell carcinoma (60-70%)
- Adenocarcinoma (15-20%)
- Esthesioneuroblastoma (rare tumor of the olfactory epithelium)
Localization
- Nasal cavity (30%)
- Maxillary sinus (60%)
- Lattice Maze (10%)
TNM stages
- T1: Tumor within the mucosa
- T4b: Invasion into the base of the skull/brain
Treatment methods for nasal cancer
1. Surgical treatment
- Endoscopic endonasal resection (for T1-T2)
- Maxillectomy with orbital preservation
- Microsurgical reconstruction (free flaps)
2. Radiation therapy
- Proton therapy (for skull base tumors)
- IMRT (sparing the salivary glands)
3. Systemic therapy
- Cisplatin+5-FU (neoadjuvant chemistry)
- Cetuximab (for relapses)
- Pembrolizumab (for PD-L1+)
Survival prognosis
- Stage I: 80-85% 5-year survival rate
- Stage III: 40-50%
- T4b: 20-25%
Factors for improving prognosis:
- HPV positive status
- Clean resection margins
Why choose Germany?
- Leader in reconstructive surgery – restoration of function in 90% of cases
- Access to clinical trials (eg immunotherapy for relapses)
Conclusion
RheinRegio Klinik Zentrum takes an interdisciplinary approach to the treatment of nasal cancer, combining the experience of oncologists, surgeons and rehabilitation specialists.
Sign up for a consultation – we will help you defeat the disease with minimal consequences!
Our clinics
The association of clinics RheinRegio Klinik Zentrum offers the organization of treatment for nasal cancer in Germany without intermediaries, providing access to the country’s leading oncology clinics. We combine advanced techniques, an individual approach and the highest level of medical care, giving hope even in difficult cases.
Why RheinRegio Klinik Zentrum?
- Expert center for rhino-oncology – performing 50+ operations annually
- Robotic surgery (Da Vinci) – for nasopharyngeal tumors
- Prosthetics of facial defects – 3D printed implants
- Rehabilitation – restoration of smell and breathing
