Treatment of uterine fibroids with adenomyosis in Germany

Innovations in the treatment of uterine fibroids with adenomyosis: from ultrasound diagnostics to organ-preserving technologies

Uterine fibroids with adenomyosis are a common combination of gynecological pathologies that require a special approach to treatment. RheinRegio Klinik Zentrum uses modern organ-preserving techniques, including uterine artery embolization (UAE) and laparoscopic surgeries, which makes it possible to effectively treat the disease while preserving reproductive function.

Symptoms of uterine fibroids with adenomyosis

The combination of these pathologies enhances clinical manifestations:

  • Heavy and painful menstruation (menorrhagia)
  • Intermenstrual bleeding
  • Chronic pelvic pain (worsening before menstruation)
  • Anemia due to blood loss
  • Disorders of urination and defecation (for large sizes)
  • Infertility or miscarriage

If these symptoms are present, an urgent consultation with a gynecologist is recommended.

Features of the disease

  • Myoma is a benign tumor of the muscular layer of the uterus
  • Adenomyosis – growth of the endometrium into the muscle layer
  • The combination of pathologies occurs in 35-50% of patients
  • Hormonal dependence (estrogen-progesterone imbalance)

Diagnosis of uterine fibroids with adenomyosis at RheinRegio Klinik Zentrum

We conduct a comprehensive examination:

  • Ultrasound with Dopplerography (transvaginal and abdominal)
  • MRI of the pelvis is the gold standard for diagnosis
  • Hysteroscopy with endometrial biopsy
  • Laboratory tests (hormonal profile, tumor markers)
  • Differential diagnosis with endometriosis and cancer

Our gynecological surgeons use the latest diagnostic protocols to accurately assess the condition.

Each direction is supervised by advanced oncologists.

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    Classification and stages of uterine fibroids with adenomyosis

    Classification by localization

    • Subserosal – grows on the outer wall of the uterus, can put pressure on the bladder/intestines.
    • Intramural – inside the muscle layer, causes an enlargement of the uterus.
    • Submucosal – under the mucous membrane, provokes bleeding.
    • Cervical – in the cervical area, rare.

    Stages of development

    • Small (up to 2–3 cm) – often asymptomatic.
    • Average (3–6 cm) – disrupt the menstrual cycle.
    • Large (>6 cm) – risk of uterine deformation, complications during pregnancy.

    Special forms

    • Myoma with adenomyosis – combination with germination of the endometrium into the muscle layer.
    • Calcified – with long-term existence.

    Why is this important?

    • Defines treatment tactics (hormones, FUS ablation, surgery).
    • Affects fertility forecast.

    Treatment methods for uterine fibroids with adenomyosis

    Conservative therapy

    • Hormonal drugs (GnRH agonists, progestogens)
    • Mirena IUD (levonorgestrel-releasing system)
    • Non-hormonal hemostatic agents for bleeding

    Minimally invasive methods

    • Uterine artery embolization (UAE) – efficiency up to 95%
    • FUS ablation – ultrasonic destruction of nodes
    • Laparoscopic myomectomy – organ-conserving surgery

    Surgical treatment

    • Hysteroresectoscopy for submucosal nodes
    • Laparoscopic hysterectomy (in difficult cases)

    Rehabilitation and restoration of fertility

    • Hormonal support after surgery
    • Planning pregnancy in 6-12 months

    Myoma with adenomyosis is not a death sentence for women’s health. At RheinRegio Klinik Zentrum, we use innovative technologies to provide our patients with effective treatment while maintaining quality of life and reproductive function.

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    Our clinics

    The association of clinics RheinRegio Klinik Zentrum offers the organization of treatment of uterine fibroids with adenomyosis in Germany without intermediaries, providing access to the country’s leading oncology clinics. We combine advanced techniques, an individual approach and the highest level of medical care, giving hope even in difficult cases.

    Catholic Clinical Complex

    The clinic specializes in the diagnosis and medical treatment of tumor diseases of internal organs (solid tumors and carcinomas), connective and musculoskeletal tissues (so-called sarcomas), as well as diseases of the blood and lymphatic system (lymphoma and leukemia). It conducts a wide range of clinical studies aimed at developing new drugs and vaccines for the treatment of cancer.

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    Rhine Clinical Complex Hospital Lucas

    The Lucas Clinic plays a key role in the German healthcare system, offering a wide range of medical services. All diagnostic and therapeutic radiological activities are carried out at the Institute of Clinical Radiology. Using the most modern devices, in accordance with the latest medical advances, low-irradiation methods of radiation therapy are used.

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    Sana’a Clinical Complex

    The Sanaa Clinical Complex actively uses the latest medical technologies in the treatment of cancer, including robotic surgical systems, high-precision diagnostics and innovative methods of radiation and chemotherapy.

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    Our oncologists:

    Bjorn-Wieland Lisboa

    Gynecologist, senologist, specialist in the treatment of breast cancer, Doctor of Medical Sciences…

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    Karl-Axel Hartmann

    A leading specialist in radiation therapy, Professor, Doctor of Medical Sciences, is included in the TOP list of the best German doctors…

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    Tobias Heintges

    Prof., dr. honey. Sciences, oncologist, gastroenterologist. Included in the TOP list of the best doctors in Germany according to the results of the annual survey of the public journalistic magazine “FOCUS”

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    Jörg Falbrede

    Gynecologist, oncologist, mammologist, uro-gynecologist, professor, doctor of medical sciences Jörg Falbrede is included in the TOP list of the best gynecologists in Germany…

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    Aristotle Giagounidis

    Professor, Doctor of Medical Sciences, Head of the Clinic of Oncology and Hematology Medicine, is on the TOP list of the best German oncologists…

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    Jan Martin Beron

    Dr. med. Jan Martin Beron, leading specialist in thoracic surgery. Specializes in the treatment of lung tumors, including lung cancer and metastases…

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    Thomas Dirschka

    Dermatologist, onco-dermatologist, specialist in allergology and venereology, professor, doctor of medical sciences…

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    Susan Ingman

    Radiologist, Diagnostic Radiologist, Nuclear Medicine Specialist, Dr. Susan Ingman, MD

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    Why RheinRegio Klinik Zentrum?

    • Gynecologists with 20 years of experience in treating complex cases
    • Own endovascular operating room for UAE
    • Organ-preserving approach in women of reproductive age
    • German diagnostic standards (DGGG)
    • Individual treatment regimens for each patient

    Application for treatment

    Apply now, and our highly qualified staff quickly and professionally choose specialized clinics and physician and prepare visa invitation from the clinic. Application processing time varies from a few hours to 2-3 working days (depending on the complexity of the inquiry).